United States securities and exchange commission logo August 14, 2023 Peter B hler Chief Financial Officer Valneva SE 6 rue Alain Bombard 44800 Saint-Herblain, France Re: Valneva SE Form 20-F for the Fiscal Year Ended December 31, 2022 Filed March 30, 2023 File No. 001-40377 Dear Peter B hler: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences